Social impact assessment of investment activities in the China–Pakistan economic corridor

In order to analyze potential social risks, and achieve smooth implementation of investment activities in the China–Pakistan economic corridor (CPEC), we attempt to establish social impact and risk indicators. Both the impacts on the projects and the impacts of the projects are used to develop risk indicators in accordance with the literature review, reality and international standard principles. Using an analytic hierarchy process (AHP) and average value to analyze questionnaires of both Chinese and Pakistani respondents, we identify the importance of various risk indicators. The primary social risks of the western high mountain region include tribal obstacles and religious extremism. The social risks to the southeast coastal plains include preserving the historical and cultural heritage of the area and international protection of national parks. The social risks in north Kashmir include disputes, extremist threats, religious and cultural differences, and the protection of natural reserves. The social risks of the Xinjiang region primarily involve social issues faced by ethnic minorities and environmental pressures.     

Occurrence and risk assessment of mycotoxins,acrylamide, and furan in Latvian beer

This work reports data on the occurrence of nine mycotoxins and two food processing contaminants – acrylamide and furan – in a total of 100 beers produced in Latvia. Mycotoxins were detected by high-performance liquid chromatography (HPLC) coupled with time-of-flight mass spectrometry, acrylamide by HPLC coupled with quadrupole-Orbitrap mass spectrometry, and furan by headspace gas chromatography-mass spectrometry. The most frequently occurring mycotoxins were HT-2 and deoxynivalenol (DON), which were detected in 52% and 51% of the analysed samples. The highest content was observed for DON, reaching the maximum of 248 µg kg^?1. Furan was ubiquitous, and 74% of the samples contained acrylamide. In terms of the estimated exposure, the biggest potential risk was identified for HT-2 representing more than 11% of tolerable weekly intake. The margin of exposure approach indicated the exposure to furan through beer as significant, this parameter being close to the critical limit.     

Stabilisation of stochastic differential equations driven by G-Brownian motion via aperiodically intermittent control

ABSTRACT

As an emerging field, the G-Itô stochastic calculus plays an important role in describing the model uncertainty. Many interesting works have been done on stochastic differential equations driven by G-Brownian motion (G-SDEs). Among the theories and applications of G-SDEs, the stability is the vital important one. In this paper, we investigate the stabilisation for G-SDEs based on G-Lyapunov function and aperiodically adaptive intermittent controller. As an application, the sufficient conditions are established for the stabilisation of stochastic Cohen–Grossberg neural networks driven by G-Brownian motion (G-SCGNNs). Finally, an example is provided to illustrate the obtained results.     

Quality-by-design approach for the development of telmisartan potassium tablets

A quality-by-design approach was adopted to develop telmisartan potassium (TP) tablets, which were bioequivalent with the commercially available Micardis^® (telmisartan free base) tablets. The dissolution pattern and impurity profile of TP tablets differed from those of Micardis^® tablets because telmisartan free base is poorly soluble in water. After identifying the quality target product profile and critical quality attributes (CQAs), drug dissolution, and impurities were predicted to be risky CQAs. To determine the exact range and cause of risks, we used the risk assessment (RA) tools, preliminary hazard analysis and failure mode and effect analysis to determine the parameters affecting drug dissolution, impurities, and formulation. The range of the design space was optimized using the face-centered central composite design among the design of experiment (DOE) methods. The binder, disintegrant, and kneading time in the wet granulation were identified as X values affecting Y values (disintegration, hardness, friability, dissolution, and impurities). After determining the design space with the desired Y values, the TP tablets were formulated and their dissolution pattern was compared with that of the reference tablet. The selected TP tablet formulated using design space showed a similar dissolution to that of Micardis^® tablets at pH 7.5. The QbD approach TP tablet was bioequivalent to Micardis^® tablets in beagle dogs.     

宽带数字接收机IQ不平衡估计与自适应补偿算法

针对宽带调制解调技术中广泛存在的IQ不平衡问题,在IQ不平衡模型及补偿原理的分析基础上提出了一种宽带数字接收机IQ不平衡估计与自适应补偿算法。首先利用解调数据对IQ不平衡参数进行实时估计,然后利用估计参数对接收信号进行自适应补偿。实验结果表明,所提算法可以有效解决宽带调制解调系统中普遍存在的IQ不平衡问题,提升系统误码性能。     

Design and analysis adaptivity in multiresolution topology optimization

Multiresolution topology optimization (MTO) methods involve decoupling of the design and analysis discretizations, such that a high-resolution design can be obtained at relatively low analysis costs. Recent studies have shown that the MTO method can be approximately 3 and 30 times faster than the traditional topology optimization method for two-dimensional (2D) and three-dimensional (3D) problems, respectively. To further exploit the potential of decoupling analysis and design, we propose a dp-adaptive MTO method, which involves locally increasing/decreasing the polynomial degree of the shape functions (p) and the design resolution (d). The adaptive refinement/coarsening is performed using a composite refinement indicator that includes criteria based on analysis error, presence of intermediate densities, as well as the occurrence of design artifacts referred to as QR-patterns. While standard MTO must rely on filtering to suppress QR-patterns, the proposed adaptive method ensures efficiently that these artifacts are suppressed in the final design, without sacrificing the design resolution. The applicability of the dp-adaptive MTO method is demonstrated on several 2D mechanical design problems. For all the cases, significant speedups in computational time are obtained. In particular for design problems involving low material volume fractions, speedups of up to a factor of 10 can be obtained over the conventional MTO method.     

Effects of Different Short-Term UV-B Radiation Intensities on Metabolic Characteristics of Porphyra haitanensis

The effects of ultraviolet (UV) radiation, particularly UV-B on algae, have become an important issue as human-caused depletion of the protecting ozone layer has been reported. In this study, the effects of different short-term UV-B radiation on the growth, physiology, and metabolism of Porphyra haitanensis were examined. The growth of P. haitanensis decreased, and the bleaching phenomenon occurred in the thalli. The contents of total amino acids, soluble sugar, total protein, and mycosporine-like amino acids (MAAs) increased under different UV-B radiation intensities. The metabolic profiles of P. haitanensis differed between the control and UV-B radiation-treated groups. Most of the differential metabolites in P. haitanensis were significantly upregulated under UV-B exposure. Short-term enhanced UV-B irradiation significantly affected amino acid metabolism, carbohydrate metabolism, glutathione metabolism, and phenylpropane biosynthesis. The contents of phenylalanine, tyrosine, threonine, and serine were increased, suggesting that amino acid metabolism can promote the synthesis of UV-absorbing substances (such as phenols and MAAs) by providing precursor substances. The contents of sucrose, D-glucose-6-phosphate, and beta-D-fructose-6-phosphate were increased, suggesting that carbohydrate metabolism contributes to maintain energy supply for metabolic activity in response to UV-B exposure. Meanwhile, dehydroascorbic acid (DHA) was also significantly upregulated, denoting effective activation of the antioxidant system. To some extent, these results provide metabolic insights into the adaptive response mechanism of P. haitanensis to short-term enhanced UV-B radiation.     

自适应融合层级特征的混合退化图像复原算法

多种退化类型混合的图像比单一类型的退化图像降质更严重,很难建立精确模型对其复原,研究端到端的神经网络算法是复原的关键.现有的基于操作选择注意力网络的算法(operation-wiseattentionnetwork,OWAN)虽然有一定的性能提升,但是其网络过于复杂,运行较慢,复原图像缺乏高频细节,整体效果也有提升的空间.针对这些问题,提出一种基于层级特征融合的自适应复原算法.该算法直接融合不同感受野分支的特征,增强复原图像的结构;用注意力机制对不同层级的特征进行动态融合,增加模型的自适应性,降低了模型冗余;另外,结合L1损失和感知损失,增强了复原图像的视觉感知效果.在DIV2K,BSD500等数据集上的实验结果表明,该算法无论是在峰值信噪比和结构相似性上的定量分析,还是在主观视觉质量方面,均优于OWAN算法,充分证明了该算法的有效性.     

No-reference quality assessment of dynamic sports videos based on a spatiotemporal motion model

This paper proposes an approach to improve the performance of no-reference video quality assessment for sports videos with dynamic motion scenes using an efficient spatiotemporal model. In the proposed method, we divide the video sequences into video blocks and apply a 3D shearlet transform that can efficiently extract primary spatiotemporal features to capture dynamic natural motion scene statistics from the incoming video blocks. The concatenation of a deep residual bidirectional gated recurrent neural network and logistic regression is used to learn the spatiotemporal correlation more robustly and predict the perceptual quality score. In addition, conditional video block-wise constraints are incorporated into the objective function to improve quality estimation performance for the entire video. The experimental results show that the proposed method extracts spatiotemporal motion information more effectively and predicts the video quality with higher accuracy than the conventional no-reference video quality assessment methods.